Casting et équipe

Adrien BrodyPsycho Ed

Matt BushHenry Burke

Sean MarquetteTravis Breaux

Colin HanksBrandon Ellis

Michael ChiklisDr. Leslie Gordon

Adhir KalyanSebastian Saleem

Mykelti WilliamsonParanoid

Luis ChávezBig Dave

Max Van VilleLittle Dave

Brett KellyMartin Gordon

George BackMalcolm

Alicia SixtosSharky Ovante

Andrew WilsonHippie Dude

Camille ManaDana

Erica Vittina PhillipsTameka

AG

Arcadiy GolubovichEdwin Hunter

Julia LingCharlyne

Cody LongoChad

Mary BirdsongMrs. Gordon

Yeardley SmithComputer Skills Teacher

Curtis ArmstrongMr. Thompson

AB

Alex BiatsSpelling Bee Rival

JB

John BeardMale News Desk Reporter

Barret SwatekFemale News Desk Reporter

Rhys CoiroVato

Wyatt RussellDrug PSA Stoned Teenager

Mike EshaqLead Terrorist

HE

Heather Elizabeth ReganCheerleader who collides with Henry

TL

Terri Lyn RodriguezVivian

Robert Bailey Jr.Jeffrey

KR

Kelli RasmusHippie Chick

SB

Shirley BenyasOlder Female Donor

Wallace BridgesAfrican American Donor

CH

Carl Harry CarlsonDonor #1

RG

Randy GodwinDonor #2

ME

Mike EvansDonor #3

Linda BostonHead Nurse

Nadine CrockerEmily Tooms

CS

Clarence SmithChess Opponent

RA

Ron AyersStunned Lawn Bowler

KM

Karl MurphyBand Teacher

Rachel QuaintanceAngry Parent #1

Peter ToccoAngry Parent #2

MW

Mike WoodsAnnouncer

KB

Kerry BirminghamFemale Reporter

KY

Kevin YonMr. Cavanaugh

Sammy A. PublesCook #1

RS

Rene SantanaCook #2

BT

Billye ThompsonCop #1

J. J. SoriaRubin

DH

David HerbstSchool Security Guard

John O'HurleyDrug PSA (voice)

John Stalberg Jr.Grandpa Frodo - Ed's Frog (voice)

HK

Heather KleisnerHenry's Mom (voice)

DD

D.B. DickersonStoned High School Student (uncredited)

SD

Sabrina DunganHigh School Student (uncredited)

PG

Penny GibbsSchool Admin (uncredited)

AL

Adam LorenzDwayne Reynolds (uncredited)

BL

Bill LumbertConcerned Parent (uncredited)

MM

Misty MillsTeacher (uncredited)

JR

Jerry ReidHigh School Student (uncredited)

SS

Steven SutherlandAcademy Student (uncredited)

JT

Joe TinpanTerrorist (uncredited)

Michael VartanCalculus Teacher (uncredited)

KJ

Kathi J. MooreLibrarian

TL

Trey LivingstonStudent (uncredited)